Influenza H3N2 Vaccines: Recent Challenges

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2018 English Publisher:Elsevier BVJournal:Trends in Microbiology, volume 26, pages 87-89 (issn: 0966-842X,

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Authors: Ahmed, Mostafa; Stephan, Pleschka;

doi: 10.1016/j.tim.2017.12.003

pmid: 29268980

Influenza H3N2 Vaccines: Recent Challenges

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Abstract

H3N2-subtype influenza A viruses are major causes of seasonal influenza epidemics. Emerging H3N2 variants require the annual adjustment of the vaccine strain. Recently, studies addressing the reduced effectiveness of current H3N2 vaccines have identified production-related substitutions in the viral hemagglutinin antigen as a possible cause for reduced vaccine efficacy.

Related Organizations

Justus Liebig University Giessen
Germany
National Research Centre
Egypt

Keywords

Influenza Vaccines, Influenza A Virus, H3N2 Subtype, Influenza, Human, Humans, Hemagglutinin Glycoproteins, Influenza Virus, Antigens, Viral

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