AI-2 to the rescue against antibiotic-induced intestinal dysbiosis?

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2015 English Publisher:Elsevier BVJournal:Trends in Microbiology, volume 23, pages 327-328 (issn: 0966-842X,

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Authors: Zhongke, Sun; Verena, Grimm; Christian U, Riedel;

doi: 10.1016/j.tim.2015.04.002

pmid: 25900476

AI-2 to the rescue against antibiotic-induced intestinal dysbiosis?

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Abstract

The downside of antibiotic treatment of infectious diseases is a disturbed intestinal microbiota leading to reduced resistance against pathogen colonization. Work by Thompson et al. now suggests that antibiotic-induced intestinal dysbiosis can partially be counterbalanced by artificially increasing the levels of autoinducer-2 (AI-2), a well-known bacterial communication molecule.

Related Organizations

University of Ulm
Germany
Zhoukou Normal University
China (People's Republic of)

Keywords

Intestines, Male, Lactones, Microbiota, Homoserine, Animals, Quorum Sensing

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