A Dopaminergic Basis for Fear Extinction

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2019 Netherlands English Publisher:Elsevier BVJournal:Trends in Cognitive Sciences, volume 23, pages 274-277 (issn: 1364-6613,

Copyright policy )Funded by:DFG | unidentified

Authors: Kalisch, R.; Gerlicher, A.M.V.; Duvarci, S.;

doi: 10.1016/j.tics.2019.01.013

pmid: 30803871

handle: 11245.1/b7eae7fb-d61b-4a91-a9e4-38fcd601392c

A Dopaminergic Basis for Fear Extinction

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Abstract

It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.

Country

Netherlands

Related Organizations

Institut für Neuropathologie
Germany
University of Amsterdam
Netherlands
University Medical Center of the Johannes Gutenberg University Mainz
Germany
Johannes Gutenberg University of Mainz
Germany
Goethe University Frankfurt
Germany

Keywords

Memory, Long-Term, 330, Dopamine, 150, Animals, Humans, Fear, Extinction, Psychological

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