1 Rheinberger, H-J. (2004) A history of protein biosynthesis andribosome research. In Protein Synthesis and Ribosome Structure(Nierhaus, K.H. and Wilson, D.N., eds), pp. 1–51, Wiley-VCH Verlag2 Green, A.A. et al. (1954) The structure of haemoglobin. IV. Signdetermination by the isomorphous replacement method. Proc. Roy.Soc. A225, 287–3073 Ban, N. et al. (2000) The complete atomic structure of the largeribosomal subunit at 2.4 A˚ resolution. Science 289, 905–9204 Wimberly, B.T. et al. (2000) Structure of the 30S ribosomal subunit.Nature 407, 327–3395 Schluenzen, F. et al. (2000) Structure of functionally activated smallribosomal subunit at 3.3 A˚ resolution. Cell 102, 615–6236 Yonath, A. et al. (1980) Crystallization of the large ribosomal subunitsfrom Bacillus stearothermophilus. Biochem. Internat. 1, 428–4357von Bohlen, K.et al. (1991) Characterization and preliminaryattempts for derivization of crystals of large ribosomal subunits fromHaloarcula marismortui diffracting to 3 A˚ resolution. J. Mol. Biol.222, 11–158 Harrison, S.C. et al. (1978) Tomato bushy stunt virus at 2.9 A˚resolution. Nature 276, 368–3739 Abad-Zapatero, C. et al. (1980) Structure of southern bean mosaicvirus at 2.8 A˚ resolution. Nature 286, 33–3910 Haas, D.J. and Rossmann, M.G. (1970) Crystallographic studies oflactate dehydrogenase at