Ring-closing metathesis in peptides

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2016 English Publisher:Elsevier BVJournal:Tetrahedron Letters, volume 57, pages 4,325-4,333 (issn: 0040-4039,

Copyright policy )Funded by:ARC | New Conus-derived alpha-c..., ARC | New metal catalysed tande...

Authors: Ellen C. Gleeson; W. Roy Jackson; Andrea J. Robinson;

doi: 10.1016/j.tetlet.2016.08.032

Ring-closing metathesis in peptides

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Abstract

Abstract This review highlights developments in the field of ring-closing metathesis applied to the synthesis of cyclic peptides. Special attention is focussed on the synthesis of dicarba peptides that mimic native cystine containing peptides. Recent advances in the field are discussed, including the stereoselective synthesis of carbon-bridged peptides and RCM in aqueous media.

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Monash University, Clayton campus
Australia
Monash University
Australia

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