Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?
Copyright policy ) van Raalte, Daniël H; Verchere, C Bruce;
Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?
Glucagon-like peptide (GLP)-1 receptor agonists enhance insulin secretion and may improve pancreatic islet cell function. However, GLP-1 receptor (GLP-1R) agonist treatment may have more complex, and sometimes deleterious, effects on beta cells. We discuss the concepts of beta cell protection versus exhaustion for different GLP-1R agonists based on recent data.
Netherlands
- Amsterdam UMC, location VUmc Netherlands
- University of British Columbia Canada
- Amsterdam UMC Netherlands
- Child and Family Research Institute Canada
Glucagon-Like Peptide-1 Receptor Agonists, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Journal Article, Animals, Humans, Insulin, Glucagon-Like Peptide-1 Receptor, Signal Transduction
Glucagon-Like Peptide-1 Receptor Agonists, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Journal Article, Animals, Humans, Insulin, Glucagon-Like Peptide-1 Receptor, Signal Transduction
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 15
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