
We show that the theory of sorting by reversals fits into the well-established theory of circuit partitions of 4-regular multigraphs (which also involves the combinatorial structures of circle graphs and delta-matroids). In this way, we expose strong connections between the two theories that have not been fully appreciated before. We also discuss a generalization of sorting by reversals involving the double-cut-and-join (DCJ) operation. Finally, we also show that the theory of sorting by reversals is closely related to that of gene assembly in ciliates.
25 pages, 16 figures
FOS: Computer and information sciences, gene assembly in ciliates, Discrete Mathematics (cs.DM), sorting by reversals, genome rearrangements, Applications of graph theory, 4-regular graphs, Sorting by reversals; Sorting by DCJ operations; Genome rearrangements; 4-Regular graphs; Local complementation; Gene assembly in ciliates, sorting by DCJ operations, Problems related to evolution, FOS: Mathematics, Mathematics - Combinatorics, local complementation, Combinatorics (math.CO), Genetics and epigenetics, Computer Science - Discrete Mathematics
FOS: Computer and information sciences, gene assembly in ciliates, Discrete Mathematics (cs.DM), sorting by reversals, genome rearrangements, Applications of graph theory, 4-regular graphs, Sorting by reversals; Sorting by DCJ operations; Genome rearrangements; 4-Regular graphs; Local complementation; Gene assembly in ciliates, sorting by DCJ operations, Problems related to evolution, FOS: Mathematics, Mathematics - Combinatorics, local complementation, Combinatorics (math.CO), Genetics and epigenetics, Computer Science - Discrete Mathematics
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