
pmid: 31703768
In this issue of Cell Stem Cell, Di Stefano et al. (2019) identify the RNA helicase DDX6 as a regulator of stem cell pluripotency and differentiation. DDX6 depletion leads to P-body disruption, which, in turn, inhibits or promotes stem and progenitor cell differentiation, depending on their cellular context.
DEAD-box RNA Helicases, Pluripotent Stem Cells, Proto-Oncogene Proteins, Cell Plasticity, Homeostasis, Cell Differentiation
DEAD-box RNA Helicases, Pluripotent Stem Cells, Proto-Oncogene Proteins, Cell Plasticity, Homeostasis, Cell Differentiation
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