Engineering Human Bone Marrow Proxies

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2018 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 22, pages 298-301 (issn: 1934-5909,

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Authors: Bourgine PE; Martin I; Schroeder T;

doi: 10.1016/j.stem.2018.01.002

pmid: 29499148

Engineering Human Bone Marrow Proxies

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Abstract

Recent advances in engineering complex organs in vitro inspire the development of human bone marrow equivalents to foster scientific discovery and innovative therapeutics. Here, we discuss challenges in generating relevant human bone marrow proxies, potential design principles, and future directions.

Related Organizations

ETH Zurich
Switzerland
University Hospital of Basel
Switzerland
University of Basel
Switzerland

Keywords

Tissue Engineering, Bone Marrow, Cell Culture Techniques, Humans, Models, Biological, Hematopoiesis

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