
pmid: 28475880
Mammalian embryonic stem cells (ESCs) can self-organize in vitro, but whether they can recreate early embryonic morphogenesis is unclear. Harrison et al. recently demonstrate in Science that 3D co-cultures of mouse ESCs and trophoblast stem cells self-organize into embryo-like structures that recreate many features of early mouse development.
Endoderm, Gastrulation, Gene Expression Regulation, Developmental, Cell Differentiation, Mouse Embryonic Stem Cells, Embryo, Mammalian, Coculture Techniques, Trophoblasts, Mice, Animals, Humans, Embryonic Stem Cells
Endoderm, Gastrulation, Gene Expression Regulation, Developmental, Cell Differentiation, Mouse Embryonic Stem Cells, Embryo, Mammalian, Coculture Techniques, Trophoblasts, Mice, Animals, Humans, Embryonic Stem Cells
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