The lncRNA Pnky in the Brain

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2015 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 16, pages 344-345 (issn: 1934-5909,

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Authors: Cho, Kyung-Ok; Hsieh, Jenny;

doi: 10.1016/j.stem.2015.03.015

pmid: 25842971

The lncRNA Pnky in the Brain

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Abstract

Long noncoding RNAs (lncRNAs) influence diverse cellular processes and have been implicated in regulating stem cell properties. Now in Cell Stem Cell, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal differentiation from neural stem cells and mediates RNA splicing through interactions with polypyrimidine tract-binding protein 1 (PTBP1).

Related Organizations

UT Southwestern Medical Center
United States
The University of Texas Southwestern Medical Center
United States
Catholic University of Korea
Korea (Republic of)

Keywords

Neurons, Brain, Cell Biology, Heterogeneous-Nuclear Ribonucleoproteins, Neural Stem Cells, Genetics, Molecular Medicine, Animals, Humans, RNA, Long Noncoding, Embryonic Stem Cells, Polypyrimidine Tract-Binding Protein

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