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-OH No! hiPSCs Misplace Their 5hmCs

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2013 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 13, pages 10-11 (issn: 1934-5909, Copyright policy )
Authors: Lowry, William E.;

doi: 10.1016/j.stem.2013.06.007

pmid: 23827705

pmc: PMC3753777

-OH No! hiPSCs Misplace Their 5hmCs

Abstract

hiPSCs and hESCs are thought to display subtle genetic and epigenetic variability. Recently in Nature Cell Biology, Wang et al. (2013) demonstrated a role for TET1 during reprogramming of human cells and showed that hiPSCs lack appropriate 5hmC marks in subtelomeric regions, contributing to epigenetic variation common to hiPSCs.

Related Organizations
Keywords

DNA-Binding Proteins, Cytosine, Proto-Oncogene Proteins, Induced Pluripotent Stem Cells, Genetics, 5-Methylcytosine, Molecular Medicine, Humans, Cell Biology

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
hybrid