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Reprogramming a Broken Heart

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2012 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 11, pages 3-4 (issn: 1934-5909, Copyright policy )
Authors: Emil M. Hansson; Kenneth R. Chien;

doi: 10.1016/j.stem.2012.06.014

pmid: 22770235

Reprogramming a Broken Heart

Abstract

Fibrosis resulting from cardiac injury presents a major challenge to restoring heart function after myocardial infarction. Two recent papers in Nature report successful in vivo reprogramming of fibroblasts to cardiomyocytes in injured mouse hearts (Qian et al., 2012; Song et al., 2012), resulting in improved cardiac function and reduced scar formation.

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Keywords

Genetics, Molecular Medicine, Cell Biology

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Top 10%
Average
Top 10%
hybrid
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