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Fine-Tuning Silencing

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2010 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 6, pages 3-4 (issn: 1934-5909, Copyright policy )
Authors: Panning, Barbara;

doi: 10.1016/j.stem.2009.12.013

pmid: 20085734

pmc: PMC4512832

Fine-Tuning Silencing

Abstract

Polycomb Repressive Complex 2 (PRC2) modifies chromatin to silence many embryonic patterning genes, restricting their expression to the appropriate cell populations. Two reports in Cell by Peng et al. (2009) and Shen et al. (2009) identify Jarid2/Jumonji, a new component of PRC2, which inhibits PRC2 enzymatic activity to fine-tune silencing.

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Keywords

Genetics, Molecular Medicine, Cell Biology

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
hybrid