TEL Me ALL
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Genetically engineered mouse models are powerful systems for dissecting the process of human leukemogenesis. In this issue of Cell Stem Cell, Schindler et al. (2009) describe the elegant use of this approach to dissect, but not completely replicate, the multistep pathogenesis of TEL-AML1(+) leukemia.
- BC Cancer Agency Canada
Oncogene Proteins, Fusion, Cell Biology, Oncogenes, ETS Translocation Variant 6 Protein, Animals, Genetically Modified, Leukemia, Myeloid, Acute, Mice, Core Binding Factor Alpha 2 Subunit, Models, Animal, Genetics, Disease Progression, Molecular Medicine, Animals, Oncogene Fusion
Oncogene Proteins, Fusion, Cell Biology, Oncogenes, ETS Translocation Variant 6 Protein, Animals, Genetically Modified, Leukemia, Myeloid, Acute, Mice, Core Binding Factor Alpha 2 Subunit, Models, Animal, Genetics, Disease Progression, Molecular Medicine, Animals, Oncogene Fusion
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