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Cell Stem Cell
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Cell Stem Cell
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Cell Stem Cell
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Self-Renewal Made Simple

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2008 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 3, pages 7-8 (issn: 1934-5909, Copyright policy )
Authors: Dunn, N. Ray;

doi: 10.1016/j.stem.2008.06.007

pmid: 18593552

Self-Renewal Made Simple

Abstract

Embryonic stem cells (ESCs) are prone to differentiation in culture, suggesting that maintenance of the pluripotent state must be actively induced. In a recent issue of Nature, Ying et al. (2008) use soluble small molecules to inhibit pro-differentiation signals and reveal ESC self-renewal as a default cell fate.

Related Organizations
Keywords

Cell Differentiation, Cell Biology, Bone Morphogenetic Protein 4, Leukemia Inhibitory Factor, Fibroblast Growth Factors, Mice, Bone Morphogenetic Proteins, Genetics, Molecular Medicine, Animals, Cell Division, Embryonic Stem Cells

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
hybrid