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Foxa2: The Rise and Fall of Dopamine Neurons

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2008 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 2, pages 110-112 (issn: 1934-5909, Copyright policy )
Authors: Arenas, Ernest;

doi: 10.1016/j.stem.2008.01.012

pmid: 18371430

Foxa2: The Rise and Fall of Dopamine Neurons

Abstract

Understanding the development and maintenance of dopamine neurons is essential to establish novel stem cell therapies and animal models of Parkinson's disease. A recent PLoS Biology report (Kittappa et al., 2007) reveals that Foxa2 regulates dopamine neuron generation and differentiation, and that aging foxa2(+/-) mice spontaneously develop Parkinsonism.

Related Organizations
Keywords

Mice, Knockout, Neurons, Dopamine, Cell Biology, Disease Models, Animal, Mice, Parkinsonian Disorders, Genetics, Hepatocyte Nuclear Factor 3-beta, Molecular Medicine, Animals, Humans

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 37
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
37
Top 10%
Top 10%
Top 10%
hybrid
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