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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao The Spine Journalarrow_drop_down
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The Spine Journal
Article . 2004 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
The Spine Journal
Article . 2005
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/j.s...
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Molecular basis of intervertebral disc degeneration

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2004 English Publisher:Elsevier BVJournal:The Spine Journal, volume 4, pages S158-S166 (issn: 1529-9430, Copyright policy )
Authors: Matthew H, Walker; D Greg, Anderson;

doi: 10.1016/j.spinee.2004.07.010

pmid: 15541661

Molecular basis of intervertebral disc degeneration

Abstract

This review will acquaint the reader with normal development, structure, and function of the intervertebral disc. The disc is composed of the vertebral endplate, nucleus pulposus, and annulus fibrosus. These three functional components all serve important purposes for health and function of the disc. Nutrition and biomechanics are also discussed. The molecular basis of disc degeneration is reviewed so that biologic approaches to the reversal and or treatment of disc degeneration may be better understood.

Related Organizations
Keywords

Osteoarthritis, Humans, Nutritional Physiological Phenomena, Spinal Diseases, Intervertebral Disc, Biomechanical Phenomena

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
117
Top 10%
Top 10%
Top 10%
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