Site response analyses must take into account the nonlinear behavior of soils. This is typically achieved using an equivalent linear approach or using numerical analyses with an appropriate constitutive model. In this work a family of hypoplastic models is proposed for use in site response analyses. These nonlinear models use a rate-type tensorial equation and are capable of reproducing plastic deformation of soils for cyclic loading under both drained and undrained conditions. A methodology for the calibration of hypoplastic parameter for dynamic loading is proposed. The hypoplastic constitutive models are implemented in a finite element code and the site response of the Lotung downhole array site is used to validate the use of hypoplastic models for site response analysis. The hypoplastic models reproduce accurately site response at the Lotung site. The advantages and disadvantages of the hypoplastic models compared to other models are discussed.