Ciona intestinalis as a model for cardiac development
Copyright policy )Ciona intestinalis as a model for cardiac development
The primitive chordate Ciona intestinalis has emerged as a significant model system for the study of heart development. The Ciona embryo employs a conserved heart gene network in the context of extremely low cell numbers and reduced genetic redundancy. Here, I review recent studies on the molecular genetics of Ciona cardiogenesis as well as classic work on heart anatomy and physiology. I also discuss the potential of employing Ciona to decipher a comprehensive chordate gene network and to determine how this network controls heart morphogenesis.
- University of California, Berkeley United States
Models, Animal, Morphogenesis, Animals, Gene Expression Regulation, Developmental, Cell Lineage, Gene Regulatory Networks, Heart, Biological Evolution, Models, Biological, Ciona intestinalis
Models, Animal, Morphogenesis, Animals, Gene Expression Regulation, Developmental, Cell Lineage, Gene Regulatory Networks, Heart, Biological Evolution, Models, Biological, Ciona intestinalis
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).109 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!