Production of GPCR and GPCR complexes for structure determination
Copyright policy )Production of GPCR and GPCR complexes for structure determination
Since the first high-resolution structure of the beta 2 adrenergic receptor (b2AR) in 2007, we have seen a growing number of G-protein-coupled receptor (GPCR) structures coming to the repertory, providing a significant progress in our understanding of the structural basis of their function. This has been achieved by the interdisciplinary collaborative work between scientists with various expertise and the development of new methodologies as well as combining and optimizing existing techniques.
- ETH Zurich Switzerland
- Paul Scherrer Institute Switzerland
Protein Conformation, Escherichia coli, Gene Expression, Humans, Crystallization, Crystallography, X-Ray, Receptors, G-Protein-Coupled
Protein Conformation, Escherichia coli, Gene Expression, Humans, Crystallization, Crystallography, X-Ray, Receptors, G-Protein-Coupled
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