
pmid: 18485695
The purpose of this article is to give a brief, yet concise overview of the current computational methods for predicting novel RNA-RNA interactions, that is interactions whose characteristic features we do not yet know. We start by briefly reviewing experimentally confirmed examples of RNA-RNA interactions before introducing computational methods for predicting RNA-RNA interactions. We will focus primarily on the interactions between different RNA molecules, that is trans RNA-RNA interactions, and will only discuss methods for predicting RNA structure, that is cis-only RNA-RNA interactions, where this helps to gain a better understanding. We conclude by discussing the merits of the different approaches and provide an outlook on probably and desirable future developments in the field.
Models, Molecular, Nucleic Acid Conformation, RNA
Models, Molecular, Nucleic Acid Conformation, RNA
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