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Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2019Publisher:Elsevier BVJournal:Revista de Gastroenterología de México (English Edition), volume 84, pages 119-122 (issn: 2255-534X,

Authors: Ulises Rodríguez-Wong; Gayne Ruby Medina-Murillo; U. Rodríguez-Medina;

doi: 10.1016/j.rgmxen.2019.01.003

pmid: 30591198

Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing

- Summary
- Subjects
- Metrics

Abstract

Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy. There were 26 patients in each group. Group A received topical diltiazem in the anal region three times a day. Group B received a placebo. Cicatrization time was documented for 6 weeks through digital photography. Mean healing time for the group treated with diltiazem was 3.19 weeks (22.33±0.884 days) and 3.92 weeks (27.44±1.130 days) for the control group (p=0.012 95% CI). At week three, the wounds in 73.07% of the patients in the diltiazem group had healed, compared with 46.15% of the patients in the control group.

Related Organizations

Universidad La Salle
Mexico
Universidad de La Salle Bajío
Mexico

Keywords

Hemorrhoidectomy, Male, Pain, Postoperative, Wound Healing, RC799-869, Diseases of the digestive system. Gastroenterology, Middle Aged, Calcium Channel Blockers, Cicatrix, Diltiazem, Postoperative Complications, Treatment Outcome, Double-Blind Method, Humans, Female, Prospective Studies

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	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average