To determine the current knowledge on the accuracy, experiences, influence of training, and potential impact on patient management of image interpretation/reporting by South African diagnostic radiographers.The majority of reviewed studies focussed on determining the accuracy of radiographers' ability to interpret radiographic images of the skeleton, chest and computed tomography scans of the head. One focussed on exploring and describing the reporting experiences of radiographers and medical practitioners. The findings of the studies cannot be generalised to all diagnostic radiographers in South Africa but are similar to reports within the international literature.The findings of this South African focused review are comparable to the international literature. Formal image interpretation by radiographers can significantly contribute in clinical practise regarding patient management. Policymakers should develop appropriate educational programmes. They should start discussing the role boundaries of radiographers that take up this role in the clinical environment.