The neutral-zone philosophy is based upon the concept that for each individual patient, there exists within the denture space a specific area where the function of the musculature will not unseat the denture and where forces generated by the tongue are neutralized by the forces generated by the lips and cheeks. The influence of tooth position and flange contour on denture stability is equal to or greater than that of any other factor. We should not be dogmatic and insist that teeth be placed over the crest of the ridge, buccal or lingual to the ridge. Teeth should be placed as dictated by the musculature, and this will vary for different patients. Positioning artificial teeth in the neutral zone achieves two objectives. First, the teeth will not interfere with the normal muscle function, and second, the forces exerted by the musculature against the dentures are more favorable for stability and retention.