Abstract Accurate simulation of the machining process is crucial to improve milling performance, especially in High-Speed Milling, where cutting parameters are pushed to the limit. Various milling critical issues can be analyzed based on accurate prediction of cutting forces, such as chatter stability, dimensional error and surface finish. Cutting force models are based on coefficients that could change with spindle speed. The evaluation of these specific coefficients at higher speed is challenging due to the frequency bandwidth of commercial force sensors. On account of this, coefficients are generally evaluated at low speed and then employed in models for different spindle speeds, possibly reducing accuracy of results. In this paper a deep investigation of cutting force coefficient at different spindle speeds has been carried out, analyzing a wide range of spindle speeds: to overcome transducer dynamics issues, dynamometer signals have been compensated thanks to an improved technique based on Kalman filter estimator. Two different coefficients identification methods have been implemented: the traditional average force method and a proposed instantaneous method based on genetic algorithm and capable of estimating cutting coefficients and tool run-out at the same time. Results show that instantaneous method is more accurate and efficient compared to the average one. On the other hand, the average method does not require compensation since it is based on average signals. Furthermore a significant change of coefficients over spindle speed is highlighted, suggesting that speed-varying coefficient should be useful to improve reliability of simulated forces.