Atractylmacrols A-E, sesquiterpenes from the rhizomes of Atractylodes macrocephala

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2018 English Publisher:Elsevier BVJournal:Phytochemistry Letters, volume 23, pages 127-131 (issn: 1874-3900,

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Authors: Shuang-Yan Wang; Lin-Fen Ding; Jia Su; Li-Yan Peng; Liu-Dong Song; Xing-De Wu;

doi: 10.1016/j.phytol.2017.11.021

Atractylmacrols A-E, sesquiterpenes from the rhizomes of Atractylodes macrocephala

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Abstract

Abstract Phytochemical investigation of the rhizomes of Atractylodes macrocephala led to the isolation of five new sesquiterpenes, atractylmacrols A-E (1-5), as well as six known eudesmane sesquiterpenes (6-11). The structures of 1-5 were determined through interpretation of their 1D and 2D NMR spectroscopic data, as well as HREIMS values. Compounds 1-5 were evaluated for their inhibitory effects on LPS-induced nitric oxide (NO) production in RAW264.7 macrophages.

Related Organizations

Kunming Institute of Botany
China (People's Republic of)
Kunming Medical University
China (People's Republic of)
Chinese Academy of Sciences
China (People's Republic of)

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