Lycopodium alkaloids from Lycopodium obscurum L. f. strictum

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2016 English Publisher:Elsevier BVJournal:Phytochemistry Letters, volume 15, pages 260-264 (issn: 1874-3900,

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Authors: Li-Jun Wang; Juan Xiong; Wei Wang; Hai-Yan Zhang; Guo-Xun Yang; Jin-Feng Hu;

doi: 10.1016/j.phytol.2016.02.001

Lycopodium alkaloids from Lycopodium obscurum L. f. strictum

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Abstract

Abstract Two new Lycopodium alkaloids, strictumines A (1) and B (2), along with 18 related known compounds were isolated from the whole plant of Lycopodium obscurum L. f. strictum. The structures of the new compounds were established by spectroscopic methods and chemical transformation. This is the first report on chemical constituents of the title plant. All the isolates were evaluated for their inhibitory activity against acetylcholinesterase (AChE), and only a few were found to show slight bioactivity.

Related Organizations

State Key Laboratory of Drug Research
China (People's Republic of)
Chinese Academy of Sciences
China (People's Republic of)
Fudan University
China (People's Republic of)
Shanghai Institute of Materia Medica
China (People's Republic of)

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