
pmid: 23790643
Microbial transformation of oleanolic acid by Rhizomucor miehei produced three metabolites. A known compound, a 30-hydroxyl derivative (queretaroic acid), and two 7β,30- and 1β,30-dihydroxylated metabolites, respectively. The action of the same fungus (R. miehei) on maslinic acid produced an olean-11-en-28,13β-olide derivative, a metabolite hydroxylated at C-30, an 11-oxo derivative, and two metabolites with an 11α,12α-epoxy group, hydroxylated or not at C-30. Their structures were elucidated by extensive analyses of their spectroscopic data, and also by chemical correlations.
Magnetic Resonance Spectroscopy, Models, Chemical, Molecular Structure, Oleanolic Acid, Rhizomucor, Biotransformation, Triterpenes
Magnetic Resonance Spectroscopy, Models, Chemical, Molecular Structure, Oleanolic Acid, Rhizomucor, Biotransformation, Triterpenes
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