
pmid: 22041666
Fifteen limonoids, meliatoosenins E-S (1-15), and 10 known compounds were isolated from the fruits of Melia toosendan. Their structures were elucidated on the basis of extensive spectroscopic methods including DEPT, HSQC, HMBC, (1)H-(1)H COSY, and ROESY experiments. All the compounds were evaluated for antiproliferative activity using A-549 and HL-60 cell lines.
Limonins, Molecular Structure, Fruit, Humans, HL-60 Cells, Melia, Drug Screening Assays, Antitumor, Antineoplastic Agents, Phytogenic, Nuclear Magnetic Resonance, Biomolecular, Drugs, Chinese Herbal
Limonins, Molecular Structure, Fruit, Humans, HL-60 Cells, Melia, Drug Screening Assays, Antitumor, Antineoplastic Agents, Phytogenic, Nuclear Magnetic Resonance, Biomolecular, Drugs, Chinese Herbal
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