Lanostane-triterpenoids from the fungus Phellinus gilvus
Copyright policy )Lanostane-triterpenoids from the fungus Phellinus gilvus
Triterpenoids gilvsins A-D (1-4), with oxygenated lanostane skeletons, were isolated from the fruiting body of Phellinus gilvus, together with two known compounds, 24-methylenelanost-8-ene-3beta, 22-diol and 5alpha-ergosta-7,22-diene-3-one. The structures of 1-4 were deduced from analysis of spectroscopic data. The absolute configuration at C-22 of 1 was determined by the modified Mosher's method and the structure of 1 was confirmed by X-ray analysis. The hypoglycemic activities of the crude extract of P. gilvus and the isolated compounds were also evaluated, but were not promising for further investigation.
Models, Molecular, Basidiomycota, Gene Expression, Complex Mixtures, Triterpenes, Cell Line, Rats, Animals, Hypoglycemic Agents, Phosphoenolpyruvate Carboxykinase (GTP), Nuclear Magnetic Resonance, Biomolecular
Models, Molecular, Basidiomycota, Gene Expression, Complex Mixtures, Triterpenes, Cell Line, Rats, Animals, Hypoglycemic Agents, Phosphoenolpyruvate Carboxykinase (GTP), Nuclear Magnetic Resonance, Biomolecular
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