Cassane Diterpenes from Caesalpinia bonduc
Copyright policy )Cassane Diterpenes from Caesalpinia bonduc
Three cassane diterpene hemiketals, caesalpinolide-C, caesalpinolide-D, caesalpinolide-E and one cassane furanoditerpene were isolated from Caesalpinia bonduc. The molecular structures were elucidated using NMR spectroscopy in combination with IR, UV and mass spectral data and relative stereochemistries were determined through ROESY correlation. The isolated compounds were tested for their antiproliferative activity against MCF-7 (breast adenocarcinoma), DU145 (prostate carcinoma), C33A (Cervical carcinoma) and Vero (African green monkey kidney fibroblast) cells.
Models, Molecular, Caesalpinia, Magnetic Resonance Spectroscopy, Molecular Structure, Chlorocebus aethiops, Animals, Humans, Diterpenes, Cell Line, Cell Proliferation
Models, Molecular, Caesalpinia, Magnetic Resonance Spectroscopy, Molecular Structure, Chlorocebus aethiops, Animals, Humans, Diterpenes, Cell Line, Cell Proliferation
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