
pmid: 18799173
Four azaphilones, named phomoeuphorbins A-D (1-4) were isolated from cultures of Phomopsis euphorbiae, an endophytic fungus isolated from Trewia nudiflora. Structures of 1-4 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. Phomoeuphorbins A and C exhibited very weak inhibitory activities against HIV replication in C8166 cells in vitro.
Magnetic Resonance Spectroscopy, Molecular Structure, Cell Survival, Fungi, HIV-1, Humans, Benzopyrans, Pigments, Biological, Virus Replication, Cell Line
Magnetic Resonance Spectroscopy, Molecular Structure, Cell Survival, Fungi, HIV-1, Humans, Benzopyrans, Pigments, Biological, Virus Replication, Cell Line
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