Metabolites from the endophytic fungus Xylaria sp. PSU-D14

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2008 English Publisher:Elsevier BVJournal:Phytochemistry, volume 69, pages 1,900-1,902 (issn: 0031-9422,

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Authors: Wipapan, Pongcharoen; Vatcharin, Rukachaisirikul; Souwalak, Phongpaichit; Till, Kühn; Matthias, Pelzing; Jariya, Sakayaroj; Walter C, Taylor;

doi: 10.1016/j.phytochem.2008.04.003

pmid: 18495187

Metabolites from the endophytic fungus Xylaria sp. PSU-D14

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Abstract

Glucoside derivatives, xylarosides A (1) and B (2), were isolated from the broth extract of the endophytic fungus Xylaria sp. PSU-D14 along with two known compounds, sordaricin (3) and 2,3-dihydro-5-hydroxy-2-methyl-4H-1-benzopyran-4-one (4). The structures were assigned by spectroscopic methods. Sordaricin (3), one of the known metabolites, exhibited moderate antifungal activity against Candida albicans ATCC90028 with a MIC value of 32 microg/ml.

Related Organizations

University of Sydney
Australia
Prince of Songkla University
Thailand
National Center for Genetic Engineering and Biotechnology
Thailand

Keywords

Magnetic Resonance Spectroscopy, Glucosides, Molecular Structure, Xylariales

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