
pmid: 16253298
An investigation of the leaves of the Madagascan Simaroubaceae Samadera madagascariensis has yielded three C18 quassinoids, 5beta,6-dihydrosamaderine A, 2-chlorosamaderine A, and samaderolactone A, and a C19 quassinoid, 3,4beta-dihydrosamaderine C, together with the known quassinoids samaderine A, samaderine B, and cedronin. The compounds isolated displayed little or no anti-tumour activity.
Plant Leaves, Magnetic Resonance Spectroscopy, Molecular Structure, Quassins, Simaroubaceae, Madagascar, Tumor Cells, Cultured, Humans, Drug Screening Assays, Antitumor, Antineoplastic Agents, Phytogenic
Plant Leaves, Magnetic Resonance Spectroscopy, Molecular Structure, Quassins, Simaroubaceae, Madagascar, Tumor Cells, Cultured, Humans, Drug Screening Assays, Antitumor, Antineoplastic Agents, Phytogenic
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