Quassinoids from the leaves of the Madagascan Simaroubaceae Samadera madagascariensis

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Dec 2005 United Kingdom English Publisher:Elsevier BVJournal:Phytochemistry, volume 66, pages 2,734-2,739 (issn: 0031-9422,

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Authors: Coombes, PH; Naidoo, D; Mulholland, DA; Randrianarivelojosia, M;

doi: 10.1016/j.phytochem.2005.09.005

pmid: 16253298

Quassinoids from the leaves of the Madagascan Simaroubaceae Samadera madagascariensis

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Abstract

An investigation of the leaves of the Madagascan Simaroubaceae Samadera madagascariensis has yielded three C18 quassinoids, 5beta,6-dihydrosamaderine A, 2-chlorosamaderine A, and samaderolactone A, and a C19 quassinoid, 3,4beta-dihydrosamaderine C, together with the known quassinoids samaderine A, samaderine B, and cedronin. The compounds isolated displayed little or no anti-tumour activity.

Country

United Kingdom

Related Organizations

University of Surrey
United Kingdom
Institut Pasteur
France
University of KwaZulu-Natal
South Africa
Institut Pasteur de Madagascar
Madagascar

Keywords

Biochemistry & Molecular Biology, Magnetic Resonance Spectroscopy, 3, INDICA, cedronin, 6-dihydrosamaderine A, Samadera madagascariensis, 2-chlorosamaderine A, SUR LES CONSTITUANTS, Madagascar, Tumor Cells, Cultured, Humans, Science & Technology, Molecular Structure, Quassins, 4 beta-dihydrosamaderine C, Plant Sciences, quassinoids, Antineoplastic Agents, Phytogenic, PLANT SCIENCES, samaderolactone A, Plant Leaves, anti-tumour activity, MEDICINAL-PLANTS, samaderine A, samaderine B, Simaroubaceae, Simaroubaceac, LECORCE, Drug Screening Assays, Antitumor, Life Sciences & Biomedicine, BIOCHEMISTRY & MOLECULAR BIOLOGY, 5 beta

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