
pmid: 16901585
The targeting, internalization and recycling of membrane receptors in response to extracellular ligands involve a series of molecular mechanisms which are beginning to be better understood. The receptor-dependent internalization of neurotensin has been widely investigated using endogenous or heterologous receptor expression systems. This review focuses on the general properties of neurotensin sequestration and on the characterization of the receptors involved in this process.
Membrane Glycoproteins, Models, Neurological, Biological Transport, Active, Nerve Tissue Proteins, Sortilin, Endocytosis, Recombinant Proteins, Adaptor Proteins, Vesicular Transport, Animals, Humans, Receptors, Neurotensin, Neurotensin
Membrane Glycoproteins, Models, Neurological, Biological Transport, Active, Nerve Tissue Proteins, Sortilin, Endocytosis, Recombinant Proteins, Adaptor Proteins, Vesicular Transport, Animals, Humans, Receptors, Neurotensin, Neurotensin
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