
pmid: 31759953
Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage. In addition to being a marker of HTN, LV geometrical changes: concentric remodeling, concentric or eccentric LV hypertrophy (LVH) are major independent risk factors for not only CVD morbidity and mortality but also for all-cause mortality and neurological pathologies. Blood pressure control with lifestyle changes and antihypertensive agents has been demonstrated to prevent and regress LVH. Herein, we provide a comprehensive review of literature on the relationship between HTN and LV geometry abnormalities with a focus on diagnosis, prognosis, pathophysiological mechanisms, and treatment approaches.
Ventricular Remodeling, Left ventricular geometry, Left ventricular hypertrophy, Blood Pressure, Remodeling, 2705 Cardiology and Cardiovascular Medicine, Ventricular Function, Left, Anti-hypertension therapy, Treatment Outcome, Risk Factors, Hypertension, Humans, Hypertrophy, Left Ventricular, Risk Reduction Behavior, Antihypertensive Agents
Ventricular Remodeling, Left ventricular geometry, Left ventricular hypertrophy, Blood Pressure, Remodeling, 2705 Cardiology and Cardiovascular Medicine, Ventricular Function, Left, Anti-hypertension therapy, Treatment Outcome, Risk Factors, Hypertension, Humans, Hypertrophy, Left Ventricular, Risk Reduction Behavior, Antihypertensive Agents
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