Update on Uterine Mesenchymal Neoplasms

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2022 English Publisher:Elsevier BVJournal:Surgical Pathology Clinics, volume 15, pages 315-340 (issn: 1875-9181,

Authors: Elizabeth C, Kertowidjojo; Jennifer A, Bennett;

doi: 10.1016/j.path.2022.02.008

pmid: 35715164

Update on Uterine Mesenchymal Neoplasms

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Abstract

This review focuses on recent advances in epithelioid and myxoid uterine mesenchymal neoplasms, a category of tumors whereby diagnostic criteria have been rapidly evolving due to advances in molecular testing. Pertinent clinicopathological and molecular features are highlighted for perivascular epithelioid cell tumors, uterine tumors resembling ovarian sex cord tumors, BCOR/BCORL1-altered high-grade endometrial stromal sarcomas, and inflammatory myofibroblastic tumors. Novel developments in epithelioid and myxoid leiomyosarcomas are briefly discussed, and differential diagnoses with key diagnostic criteria are provided for morphologic mimickers.

Related Organizations

University of Chicago Medicine Comprehensive Cancer Center
United States
University of Chicago Medical Center
United States

Keywords

Leiomyosarcoma, Sarcoma, Endometrial Stromal, Uterine Neoplasms, Biomarkers, Tumor, Humans, Sex Cord-Gonadal Stromal Tumors, Female, Endometrial Neoplasms

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