
Lobular carcinoma in situ (LCIS) is a risk factor and a nonobligate precursor of breast carcinoma. The relative risk of invasive carcinoma after classic LCIS diagnosis is approximately 9 to 10 times that of the general population. Classic LCIS diagnosed on core biopsy with concordant imaging and pathologic findings does not mandate surgical excision, and margin status is not reported. The identification of variant LCIS in a needle core biopsy specimen mandates surgical excision, regardless of radiologic-pathologic concordance. The presence of variant LCIS close to the surgical margin of a resection specimen is reported, and reexcision should be considered.
Disease Management, Margins of Excision, Unnecessary Procedures, Mastectomy, Segmental, Carcinoma, Lobular, Humans, Female, Biopsy, Large-Core Needle, Breast Carcinoma In Situ, Watchful Waiting, Precancerous Conditions
Disease Management, Margins of Excision, Unnecessary Procedures, Mastectomy, Segmental, Carcinoma, Lobular, Humans, Female, Biopsy, Large-Core Needle, Breast Carcinoma In Situ, Watchful Waiting, Precancerous Conditions
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 76 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 1% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
