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Innate Immunity

Name: Innate Immunity
Keywords: Innate immunity, Cystic Fibrosis, Rhinosinusitis, Toll-Like Receptors, Cigarette smoke, Cystic Fibrosis Transmembrane Conductance Regulator, 1103 Clinical Sciences, Cystic fibrosis, Immunity, Innate, Toll-like receptors

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2010 Australia English Publisher:Elsevier BVJournal:Otolaryngologic Clinics of North America, volume 43, pages 473-487 (issn: 0030-6665,

Authors: Ooi, Eng Hooi; Psaltis, Alkis; Witterick, Ian J; Wormald, Peter John;

doi: 10.1016/j.otc.2010.02.020

pmid: 20525504

handle: 2440/61543 , 2328/32568

Innate Immunity

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Abstract

Innate immunity is an exciting area of research in rhinology because emerging evidence suggests that abnormal local immune responses, rather than pathogen-specific adaptive immunity, may play a more important role in the pathogenesis of chronic rhinosinusitis (CRS). This article reviews important recent research regarding the innate immune system and CRS, with particular focus on the role of pattern recognition receptors, antimicrobial peptides and biofilms, epithelial ciliary function, cystic fibrosis, and cigarette smoking, and on areas for future research and therapy.

Country

Australia

Related Organizations

Keywords

Innate immunity, Cystic Fibrosis, Rhinosinusitis, Toll-Like Receptors, Cigarette smoke, Cystic Fibrosis Transmembrane Conductance Regulator, 1103 Clinical Sciences, Cystic fibrosis, Immunity, Innate, Toll-like receptors, Mucus, Mucociliary Clearance, Biofilms, Cytokines, Homeostasis, Humans, Point Mutation, Sinusitis, Rhinitis

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	32
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%