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Ophthalmology
Article
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Ophthalmology
Article . 2012 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
British Journal of Ophthalmology
Article . 2002 . Peer-reviewed
Data sources: Crossref
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IOP Measurement and Central Corneal Thickness

Authors: Richard, Stodtmeister;

IOP Measurement and Central Corneal Thickness

Abstract

In the recent paper by Feltgen and colleagues,1 the intraocular pressure (IOP) was measured by Goldmann applanation tonometry and by using a cannula inserted into the anterior chamber connected with a pressure transducer. Thus, the measurement took place omitting a possible influence of the cornea on the result. Marx et al 2 believed that by intracameral measurement the “true” intraocular pressure may be measured. Feltgen et al share his opinion. They believe, therefore, that they have compared the intraocular pressure measured with and without the possible influence of the cornea. Feltgen et al write in their conclusion: “There is no systematic error of applanation tonometry with increasing central corneal thickness (CCT). Therefore it is inadequate to recalculate IOP based on regression formula of applanatory IOP versus CCT.” They base their conclusion on their results. In our opinion their paper shows the following methodological deficits: (1) Both methods used for measuring IOP are not up to the demands of the scientific technique of measurement; (2) their intracamerally measured IOP values do not reflect the true IOP because of bias; (3) a non-significant regression coefficient does not prove that the slope is actually 0 and, therefore, by a non-significant regression coefficient it is not proved that applanatory readings are not influenced by CCT; (4) the goodness of fit of the linear regression model is insufficient; and (5) an important covariate (true IOP value) was omitted in the linear regression. We would like to discuss these points in detail. In the study of Feltgen et al the only criterion for the quality of measurement is the stability of the readings on the monitor. However, it is not sufficient to conclude from the presence of stability that the scale readings represent the “true” pressure value that is at the tip of the cannula. …

Related Organizations
Keywords

Cornea, Male, Tonometry, Ocular, Models, Statistical, Optic Nerve Diseases, Humans, Female, Glaucoma, Open-Angle, Intraocular Pressure

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
28
Average
Top 10%
Top 10%
bronze