a Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Box #29, Brooklyn, NY 11203, USA b Medical Department, Brookhaven National Laboratory, New York, USA c University of Florida, College of Medicine, Department of Pediatrics, Gainesville, Florida, USA d University of Miami School of Medicine, Department of Pediatrics, Miami, Florida, USA e University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA f Karolinska Institute, Dept Clinical Neuroscience, Psychiatry Section, Stockholm, Sweden g National Institute on Drug Abuse, Bethesda, Maryland, USA