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Neuron
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Neuron
Article . 2017 . Peer-reviewed
License: Elsevier Non-Commercial
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SCA31 Flies Perform in a Balancing Act between RAN Translation and RNA-Binding Proteins

Authors: George R, Jackson;

SCA31 Flies Perform in a Balancing Act between RAN Translation and RNA-Binding Proteins

Abstract

In this issue of Neuron, Ishiguro et al. (2017) explore the toxicity of RAN translation in spinocerebellar ataxia 31. Using a Drosophila model, the authors demonstrate that TDP-43 and other RNA-binding proteins act as chaperones to regulate the formation of toxic RNA aggregates.

Related Organizations
Keywords

DNA-Binding Proteins, Animals, RNA, RNA-Binding Proteins, Spinocerebellar Ataxias, Drosophila

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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
hybrid