Autophagosome Formation by Endophilin Keeps Synapses in Shape

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2016 English Publisher:Elsevier BVJournal:Neuron, volume 92, pages 675-677 (issn: 0896-6273,

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Authors: Marijn, Kuijpers; Volker, Haucke;

doi: 10.1016/j.neuron.2016.11.016

pmid: 27883898

Autophagosome Formation by Endophilin Keeps Synapses in Shape

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Abstract

Soukup et al. (2016), in this issue of Neuron, and Murdoch et al. (2016), in Cell Reports, reveal an unexpected function for the endocytic protein endophilin in autophagosome formation at synapses: preventing neurodegeneration and ataxia.

Related Organizations

Leibniz Association
Germany
Leibniz Institute for Neurobiology
Germany

Keywords

Neurons, Synapses, Autophagosomes, Autophagy, Adaptor Proteins, Signal Transducing

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