Linking the VPS35 and EIF4G1 Pathways in Parkinson’s Disease

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2015 English Publisher:Elsevier BVJournal:Neuron, volume 85, pages 1-3 (issn: 0896-6273,

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Authors: Ross, Owen A.; Cook, Casey; Petrucelli, Leonard;

doi: 10.1016/j.neuron.2014.12.045

pmid: 25569341

Linking the VPS35 and EIF4G1 Pathways in Parkinson’s Disease

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Abstract

Elucidating the underlying pathogenic pathways in Parkinson's disease will be critical for targeted drug development. In this issue of Neuron, Dhungel et al. (2015) utilize a yeast model to establish a link between VPS35 and EIF4G1 in α-synuclein-related neurodegeneration.

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Mayo Clinic
United States
Mayo Clinic
United States
Mayo Clinic
United States

Keywords

Saccharomyces cerevisiae Proteins, Neuroscience(all), Vesicular Transport Proteins, alpha-Synuclein, Animals, Parkinson Disease, Caenorhabditis elegans Proteins, Eukaryotic Initiation Factor-4G

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