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Bringing Optogenetics to the Synapse

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2013 English Publisher:Elsevier BVJournal:Neuron, volume 79, pages 209-210 (issn: 0896-6273, Copyright policy )
Authors: Ehud Y. Isacoff; Ehud Y. Isacoff; Ehud Y. Isacoff; Andreas Reiner; Joshua Levitz; Joshua Levitz;

doi: 10.1016/j.neuron.2013.07.009

pmid: 23889927

Bringing Optogenetics to the Synapse

Abstract

In this issue of Neuron, Lin et al. (2013) describe InSynC, an optogenetic approach that utilizes chromophore-assisted light inactivation (CALI) to inactivate presynaptic neurotransmitter release proteins VAMP2 and synaptophysin. InSynC selectively reduces synaptic transmission in illuminated regions in vitro and in vivo.

Related Organizations
Keywords

Optogenetics, Chromophore-Assisted Light Inactivation, Neuroscience(all), Synapses, Animals, Neural Inhibition, Synaptic Transmission

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 7
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Average
Average
Average
hybrid
Related to Research communities
Neuroscience