RAN Translation: Fragile X in the Running

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2013 English Publisher:Elsevier BVJournal:Neuron, volume 78, pages 405-408 (issn: 0896-6273,

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Authors: Reddy, Kaalak; Pearson, Christopher E.;

doi: 10.1016/j.neuron.2013.04.034

pmid: 23664607

RAN Translation: Fragile X in the Running

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Abstract

In this issue of Neuron, Todd et al. (2013) reveal that noncanonical repeat associated non-AUG (RAN) translation occurs on nonexpanded (CGG)30-50 and premutation (CGG)59-160 repeats, associated with the FMR1 gene, suggesting that the polyglycine and polyalanine products might have natural and pathogenic roles.

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Keywords

Neuroscience(all)

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