Silent Synapses Sit and Wait for a Better Day
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Synaptic activity is thought to be critical for synaptic stabilization. In this issue of Neuron, Krishnaswamy and Cooper show that nicotinic synapses on autonomic neurons remain intact without synaptic activity. Postsynaptic responses are required, however, for presynaptic terminals to acquire the high-affinity choline transporter necessary for high-frequency transmission.
- University of California, San Diego United States
- University of California, San Diego United States
Neuroscience(all), Synapses, Presynaptic Terminals, Animals, Humans, Membrane Transport Proteins, Superior Cervical Ganglion, Receptors, Nicotinic, Ganglia, Autonomic, Synaptic Transmission, Acetylcholine
Neuroscience(all), Synapses, Presynaptic Terminals, Animals, Humans, Membrane Transport Proteins, Superior Cervical Ganglion, Receptors, Nicotinic, Ganglia, Autonomic, Synaptic Transmission, Acetylcholine
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