
pmid: 15946864
We present a general method for automatic meta-analyses in neuroscience and apply it on text data from published functional imaging studies to extract main functions associated with a brain area-the posterior cingulate cortex (PCC). Abstracts from PubMed are downloaded, words extracted and converted to a bag-of-words matrix representation. The combined data are analyzed with hierarchical non-negative matrix factorization. We find that the prominent themes in the PCC corpus are episodic memory retrieval and pain. We further characterize the distribution in PCC of the Talairach coordinates available in some of the articles. This shows a tendency to functional segregation between memory and pain components where memory activations are predominantly in the caudal part and pain in the rostral part of PCC.
Cerebral Cortex, Brain Mapping, neuroimaging, Databases, Factual, Emotions, Pain, text mining, Gyrus Cinguli, Stress Disorders, Post-Traumatic, Memory, magnetic resonance imaging, Humans, Radionuclide Imaging, Algorithms
Cerebral Cortex, Brain Mapping, neuroimaging, Databases, Factual, Emotions, Pain, text mining, Gyrus Cinguli, Stress Disorders, Post-Traumatic, Memory, magnetic resonance imaging, Humans, Radionuclide Imaging, Algorithms
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 154 | |
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
