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Neuroscience Research
Article . 2019 . Peer-reviewed
License: CC BY
Data sources: Crossref
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Neuroscience Research
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License: CC BY
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The mouse posterior parietal cortex: Anatomy and functions

Authors: Dmitry Lyamzin; Andrea Benucci;

The mouse posterior parietal cortex: Anatomy and functions

Abstract

In recent years, the number of studies on decision-making in mice has increased dramatically. Many of these studies focus on the posterior parietal cortex (PPC), an area that has been implicated in sensory and multisensory processing, navigation, motion planning, and decision-making. In this review we summarize recent anatomical and functional studies of mouse PPC. First, we make a note of the existing variability in the nomenclature and its anatomical localization. Based on the commonalities across different studies we then describe the connectivity of PPC and discuss its place within several functional brain networks. In view of the examined connectivity, we go on to discuss the role of PPC for the encoding of single-modality and multimodal stimuli as well as its role in navigation. Finally, we summarize the literature on the choice-related activity: we discuss the variety of behavioral protocols and sensory modalities used in these studies, and we note that the response properties of PPC and its causal involvement in decision-making may depend substantially on these conditions. We conclude that, although more research should be devoted to creating a more complete and consistent image of the mouse PPC, this area should rightfully be considered a convenient model system for a circuit-level understanding of the mammalian parietal cortex.

Related Organizations
Keywords

Mice, Parietal Lobe, Decision Making, Visual Perception, Animals

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
110
Top 1%
Top 10%
Top 1%
gold